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Welcome to SCIAN-Lab


... the Laboratory for Scientific Image Analysis.
... imaging from the southern cone.


The Laboratory of Scientific Image Analysis (SCIAN-Lab) develops mathematical tools and computational algorithms to access dynamic, morphologic, and topologic features in experimental systems with a biophysical, biological, or medical background. High speed confocal microscopy in combination with image processing routines unravels the interplay between structure and function in lipid model systems and phenomena on sub-cellular, cellular, and supra-cellular levels in the field of developmental biology, neurobiology, or membrane biophysics.

|News|
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Finally Online: Confined Displacement Algorithm (CDA)


Online Version: calculate true and random colocalization on our web page.
-> go and try it out ...

ImageJ Plugin: calculate true and random colocalization with ImageJ.
-> download the ImageJ Plugin here ...  

ImageJ: Image Processing and Analysis in Java.
-> download ImageJ here ...

The CDA has been published recenlty:
Ramirez O, García A, Rojas R, Couve A & S Härtel (2010) Confined Displacement Algorithm Determines True and Random Colocalization in Fluorescence Microscopy. Journal of Microscopy, in press

CDA has been applied in previous versions in:
Ramirez O, Vidal R, Tello J, Vargas K, Kindler S, Härtel S & A Couve (2009) Dendritic Assembly of Heteromeric Gabab Receptor Subunits in Hippocampal Neurons. JBC 8;284(19):13077-85.

Espinosa A, Garcia A, Härtel S, Hidalgo C & E Jaimovich (2009) NADPH Oxidase and Hydrogen Peroxide Mediate Insulin-induced Calcium Increase in Skeletal Muscle Cells. JBC. 284, pp:2568-2575.

Parra V, Eisner V, Chiong M, Criollo A, Moraga F, Garcia A, Härtel S, Jaimovich E, Zorzano A, Hidalgo C & S Lavandero (2008) NADPH Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc Res. 77(2), pp:387-97.

Sánchez G, Escobar M, Pedrozo Z, Macho P, Domenech R, Härtel S, Hidalgo C, Donoso P (2008) Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection. Cardiovasc Res. 77(2), pp:380-6.
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Curso y Taller Internacional: Microscopía de Fluorescencia

-> more information
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SCMI: Startup Conference Medical Informatics

-> more information
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SCMI: Startup Conference Medical Informatics: Biología-Informática-Medicina
Sesión de Póster y Exposición de Proyectos de Investigación y Desarrollo


-> more information
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Curso Electivo Teórico-Práctico | 23/07-03/08/2009 - Santiago - Chile |

-> more information
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Lipids are fun ...

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XI Curso Avanzado de Microscopia Celular Integral
| 03-15/11/2008 - Santiago - Chile |


-> more information
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Curso Electivo Teórico-Práctico | 23/07-04/08/2008 - Santiago - Chile |

-> more information
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se busca tesista y asistente de investigación / open positions:
-> research assistant.
-> student thesis.
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Ganador Concurso Tesis Digitales 2007

Con la tesis Contornos Activos en Tres Dimensiones para la Segmentación de Estructuras Biológicas, el Ingeniero Civil en Informática, Jorge Jara, ganó el Concurso Tesis Digitales 2007 ortogado por Universia Chile y Fundación País Digital.
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Premio Nikon-Ivens | Mejor Imagen en Biología Celular 2007 |

Luisa Pereiro et al: Migración Celular Durante el Desarrollo Embrionario de un Pez Anual
Sociedad de Biología Celular de Chile, XXI Reunión Anual 7-10 Octubre 2007, Pucón, Chile
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Finalista Concurso Tesis Digitales 2007

Con la tesis Contornos Activos en Tres Dimensiones para la Segmentación de Estructuras Biológicas, el Ingeniero Civil en Informática, Jorge Jara, fue selecionado entre los seis finalistas del Concurso Tesis Digitales 2007 ortogado por Universia Chile y Fundación País Digital.
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X Curso Avanzado de Microscopia Celular Integral
| 05-17/11/2007 - Santiago - Chile |


-> more information
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Curso Electivo Teórico-Práctico | 10-17/08/2007 - Santiago - Chile |

-> more information
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International Course | 16-28/04/2007 - Santiago - Chile |

Sponsors

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Medalla al Mérito Científico y Tecnológico | 30/11/2006 - Valdivia - Chile |

otogado por la Facultad de Ciencias de la Ingeniería, Universidad Austral de Chile, al Ingeniero Civil en Informática, Jorge Jara, por la 'Aplicación del Tema de Tesis a Trabajos y Publicaciones del Ambito Científico'. ___________________________________________________________

Premio Nikon-Ivens | Mejor Imagen en Biología Celular 2006 |

Steffen Härtel et al: Morfogénesis Asimétrica del Organo Parapineal de Pez Cebra
Sociedad de Biología Celular de Chile, XX Reunión Anual 8-12 Octubre 2006, Pucón, Chile ___________________________________________________________

Open Positions:
-> research assistant.
-> student thesis.
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SCIAN resources and services offer partial or integral image analysis modules for science and education. Please visit our 'Online Processing' section where you can upload, process, view, or download images from and to any computer. The section contains a series of educative filters and a first scientific procedure for the calculation of local colocalization coefficients in fluorescent image pairs. Registered users obtain direct access to our advanced image processing modules. SCIAN's competence includes the following areas:
  • Image Restoration.
  • Object Segmentation.
  • 2|3D Object Reconstruction.
  • Pattern Recognition.
  • Object Classification.
  • Colocalization.
Please visit our site for further information or contact us.



Universidad de Chile Conicyt Xperts Explora Centro de Estudios Científicos